At times in life we feel that it is over and we cannot move on again. Looking left and right but there is no one to look up, it is then dawn on us to run to Allah first as He is the one that knows all that happens to us.
To move on from difficult situation it is stated in a hadith that
لَا حَوْلَ وَلَا قُوَّةَ إِلَّا بِاللَّهِ- There is no power except from Allah.
is the medicine for 99 ailments, the least of which is depression.
(Baihaqi in Dawatul Kubra)
It means that these words are so beneficial and useful that big/great grievances, depression and sorrow are easily removed in its stride.